Scoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activity. [electronic resource]
Producer: 20140707Description: e80391 p. digitalISSN:- 1932-6203
- Animals
- Antineoplastic Agents -- pharmacology
- Artemisia -- chemistry
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Coumarins -- pharmacology
- Cyclin D1 -- metabolism
- G1 Phase -- drug effects
- HCT116 Cells
- HT29 Cells
- HeLa Cells
- Hep G2 Cells
- Humans
- Inhibitor of Apoptosis Proteins -- metabolism
- Interleukin-6 -- metabolism
- Janus Kinase 2 -- metabolism
- MCF-7 Cells
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Phosphorylation -- drug effects
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Proto-Oncogene Proteins c-myc -- metabolism
- STAT3 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Suppressor of Cytokine Signaling 3 Protein
- Suppressor of Cytokine Signaling Proteins -- metabolism
- Survivin
- Transcription, Genetic -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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