Intrathecal ultra-low dose naloxone enhances the antihyperalgesic effects of morphine and attenuates tumor necrosis factor-α and tumor necrosis factor-α receptor 1 expression in the dorsal horn of rats with partial sciatic nerve transection. [electronic resource]
Producer: 20140116Description: 1493-502 p. digitalISSN:- 1526-7598
- Analgesics, Opioid -- administration & dosage
- Animals
- Aspartic Acid -- metabolism
- Behavior, Animal -- drug effects
- Disease Models, Animal
- Down-Regulation
- Drug Synergism
- Glutamic Acid -- metabolism
- Hyperalgesia -- drug therapy
- Injections, Spinal
- Male
- Morphine -- administration & dosage
- Naloxone -- administration & dosage
- Narcotic Antagonists -- administration & dosage
- Pain Threshold -- drug effects
- Posterior Horn Cells -- drug effects
- Rats
- Rats, Wistar
- Reaction Time -- drug effects
- Receptors, Tumor Necrosis Factor, Type I -- drug effects
- Receptors, Tumor Necrosis Factor, Type II -- drug effects
- Sciatic Nerve -- surgery
- Sciatica -- drug therapy
- Time Factors
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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