Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex. [electronic resource]
Producer: 20140318Description: 348-61 p. digitalISSN:- 1098-5549
- Animals
- Cells, Cultured
- Embryo, Mammalian -- cytology
- Fibroblasts -- cytology
- Focal Adhesion Kinase 1 -- genetics
- GRB2 Adaptor Protein -- genetics
- Immunoblotting
- Integrins -- metabolism
- Mice
- Mice, Knockout
- Paxillin -- genetics
- Phosphorylation
- Protein Binding
- RNA Interference
- Receptor-Like Protein Tyrosine Phosphatases, Class 4 -- genetics
- Signal Transduction
- Tyrosine -- genetics
- src Homology Domains
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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