Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia. [electronic resource]
Producer: 20140430Description: 600-8 p. digitalISSN:- 1476-5551
- Apoptosis -- drug effects
- Child
- Chromatin Immunoprecipitation
- Core Binding Factor Alpha 2 Subunit -- genetics
- Humans
- Imidazoles -- pharmacology
- Piperazines -- pharmacology
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Proto-Oncogene Proteins c-ets -- genetics
- Proto-Oncogene Proteins c-mdm2 -- genetics
- Real-Time Polymerase Chain Reaction
- Repressor Proteins -- genetics
- Signal Transduction
- Transcription, Genetic
- Tumor Suppressor Protein p53 -- genetics
- ETS Translocation Variant 6 Protein
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.