FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease. [electronic resource]
Producer: 20140610Description: 1309-20 p. digitalISSN:- 1552-454X
- Alzheimer Disease -- drug therapy
- Bacterial Proteins -- chemistry
- Calcium Signaling -- drug effects
- Calmodulin-Binding Proteins -- chemistry
- Carbachol -- pharmacology
- Drug Evaluation, Preclinical -- methods
- Endoplasmic Reticulum -- drug effects
- Fluorescence Resonance Energy Transfer
- Fluorescent Dyes -- chemistry
- Green Fluorescent Proteins -- chemistry
- HEK293 Cells
- High-Throughput Screening Assays -- methods
- Homeostasis
- Humans
- Luminescent Proteins -- chemistry
- Microscopy, Fluorescence
- Phenotype
- Recombinant Fusion Proteins -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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