Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway. [electronic resource]
Producer: 20150223Description: e78284 p. digitalISSN:- 1932-6203
- Animals
- Apoptosis -- drug effects
- Cell Death -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Glucose -- metabolism
- Hyperuricemia -- metabolism
- Insulin -- metabolism
- Insulin-Secreting Cells -- drug effects
- Islets of Langerhans -- drug effects
- Male
- Mice
- Mice, Inbred BALB C
- NF-kappa B -- metabolism
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Signal Transduction -- drug effects
- Uric Acid -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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