Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin. [electronic resource]
Producer: 20140812Description: 35-42 p. digitalISSN:- 1791-244X
- 3-Iodobenzylguanidine -- pharmacology
- Acetylation
- Antineoplastic Agents -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor -- drug effects
- Humans
- Metformin -- pharmacology
- Mitochondria -- drug effects
- N-Myc Proto-Oncogene Protein
- Neuroblastoma -- therapy
- Nuclear Proteins -- genetics
- Oncogene Proteins -- genetics
- Phenformin -- pharmacology
- Proto-Oncogene Proteins c-myc -- genetics
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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