LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. [electronic resource]
Producer: 20140903Description: 381-6 p. digitalISSN:- 1095-953X
- Adult
- Aged
- DNA Damage
- DNA Repair
- DNA, Mitochondrial -- genetics
- Female
- Humans
- Induced Pluripotent Stem Cells -- metabolism
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Male
- Middle Aged
- Mutation
- Neural Stem Cells -- metabolism
- Parkinson Disease -- genetics
- Protein Serine-Threonine Kinases -- genetics
- Targeted Gene Repair
- Zinc Fingers
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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