Valproic acid treatment inhibits hypoxia-inducible factor 1α accumulation and protects against burn-induced gut barrier dysfunction in a rodent model. [electronic resource]
Producer: 20140805Description: e77523 p. digitalISSN:- 1932-6203
- Acetylation -- drug effects
- Animals
- Burns -- complications
- Caco-2 Cells
- Disease Models, Animal
- Gastroenteritis -- drug therapy
- Histones -- metabolism
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Intestinal Mucosa -- drug effects
- Male
- Myosin-Light-Chain Kinase -- metabolism
- Permeability -- drug effects
- Protective Agents -- administration & dosage
- Rats
- Valproic Acid -- administration & dosage
- Vascular Endothelial Growth Factor A -- metabolism
- Zonula Occludens-1 Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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