CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy. [electronic resource]
Producer: 20140604Description: 258-67 p. digitalISSN:- 1365-2249
- Antigens, CD -- metabolism
- Antigens, Differentiation, T-Lymphocyte -- metabolism
- Antigens, Neoplasm -- immunology
- CD3 Complex -- genetics
- Cell Line
- HEK293 Cells
- Humans
- Immunoreceptor Tyrosine-Based Activation Motif -- genetics
- Immunotherapy, Adoptive -- methods
- Jurkat Cells
- Lectins, C-Type -- metabolism
- Lymphocyte Activation
- Neoplasms -- immunology
- Receptors, Antigen, T-Cell -- genetics
- Recombinant Fusion Proteins -- genetics
- Signal Transduction -- immunology
- T-Lymphocytes -- immunology
- Transcriptional Activation -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.