IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway. [electronic resource]
Producer: 20140312Description: e842 p. digitalISSN:- 2041-4889
- Animals
- Autophagy -- drug effects
- Breast Neoplasms -- enzymology
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Female
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- metabolism
- Humans
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Models, Biological
- Multiprotein Complexes -- metabolism
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Organothiophosphorus Compounds -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
- Vacuoles -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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