Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain. [electronic resource]
Producer: 20140310Description: 7772-87 p. digitalISSN:- 1520-4804
- Alanine -- analogs & derivatives
- Animals
- Antibodies, Monoclonal -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Caspase 3 -- metabolism
- Caspase 7 -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Crystallography, X-Ray
- Female
- Heterocyclic Compounds -- chemical synthesis
- Humans
- Inhibitor of Apoptosis Proteins -- antagonists & inhibitors
- Mice
- Mice, Nude
- Models, Chemical
- Models, Molecular
- Molecular Structure
- Oxazepines -- chemical synthesis
- Protein Structure, Tertiary
- Rats
- Ubiquitin-Protein Ligases
- X-Linked Inhibitor of Apoptosis Protein -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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