p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway. [electronic resource]
Producer: 20131209Description: E3997-4006 p. digitalISSN:- 1091-6490
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- DNA, Complementary -- biosynthesis
- DNA, Viral -- biosynthesis
- Deoxyribonucleotides -- biosynthesis
- Down-Regulation -- genetics
- E2F1 Transcription Factor -- genetics
- Gene Expression Regulation, Enzymologic
- HIV Infections -- metabolism
- HIV-1 -- physiology
- Macrophages -- metabolism
- Monomeric GTP-Binding Proteins -- genetics
- Ribonucleotide Reductases -- biosynthesis
- SAM Domain and HD Domain-Containing Protein 1
- Simian Immunodeficiency Virus -- physiology
- Transcription, Genetic -- genetics
- Virus Replication -- physiology
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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