Jak/STAT and PI3K signaling pathways have both common and distinct roles in IL-7-mediated activities in human CD8+ T cells. [electronic resource]
Producer: 20140306Description: 117-27 p. digitalISSN:- 1938-3673
- CD8-Positive T-Lymphocytes -- drug effects
- Enzyme Activation -- drug effects
- Glucose -- metabolism
- Humans
- Interleukin-7 -- pharmacology
- Janus Kinases -- metabolism
- Mitogen-Activated Protein Kinases -- metabolism
- Perforin -- biosynthesis
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- STAT Transcription Factors -- metabolism
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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