Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice. [electronic resource]
Producer: 20140508Description: e74706 p. digitalISSN:- 1932-6203
- Analgesia
- Analgesics, Opioid -- pharmacology
- Animals
- Constipation -- chemically induced
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)- -- pharmacology
- Female
- Gene Deletion
- Gene Expression
- Gene Knockout Techniques
- Gene Order
- Gene Targeting
- Guanosine 5'-O-(3-Thiotriphosphate) -- metabolism
- Male
- Mice
- Mice, Knockout
- Morphine -- adverse effects
- NAV1.8 Voltage-Gated Sodium Channel -- genetics
- Nociception -- drug effects
- Pain -- drug therapy
- Pain Measurement
- Posterior Horn Cells -- drug effects
- Protein Binding
- Receptors, Opioid, mu -- agonists
- Sensory Thresholds -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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