Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitro. [electronic resource]
Producer: 20140908Description: 35-46 p. digitalISSN:- 1460-2377
- Animals
- Hepatocytes -- immunology
- Immune System -- immunology
- Immunity, Innate -- genetics
- Interleukin-10 -- genetics
- Interleukin-6 -- genetics
- Liver
- Mice
- Mice, Inbred C57BL
- RNA, Messenger -- genetics
- RNA, Small Interfering -- chemistry
- Toll-Like Receptors -- genetics
- Transfection -- methods
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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