Comparison of the anti-tumor effects of denosumab and zoledronic acid on the neoplastic stromal cells of giant cell tumor of bone. [electronic resource]
Producer: 20140618Description: 439-49 p. digitalISSN:- 1607-8438
- Alkaline Phosphatase -- metabolism
- Antibodies, Monoclonal, Humanized -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Count
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Collagen Type I -- genetics
- Denosumab
- Diphosphonates -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Giant Cell Tumor of Bone -- drug therapy
- Humans
- Imidazoles -- pharmacology
- Macrophage Colony-Stimulating Factor -- metabolism
- Osteoprotegerin -- genetics
- RANK Ligand -- genetics
- RNA, Messenger -- genetics
- Solubility
- Stromal Cells -- drug effects
- Zoledronic Acid
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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