The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5. [electronic resource]
Producer: 20131216Description: 1101-8 p. digitalISSN:- 1526-7598
- Absorption
- Anesthetics, Local -- adverse effects
- Bupivacaine -- adverse effects
- Dose-Response Relationship, Drug
- Drug Combinations
- Electrophysiology
- Emulsions -- pharmacology
- Fat Emulsions, Intravenous -- pharmacology
- HEK293 Cells
- Humans
- Inhibitory Concentration 50
- Kidney -- drug effects
- Lipids -- chemistry
- NAV1.5 Voltage-Gated Sodium Channel -- drug effects
- Patch-Clamp Techniques
- Phospholipids -- pharmacology
- Sodium Channel Blockers -- pharmacology
- Sorbitol -- pharmacology
- Soybean Oil -- pharmacology
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Publication Type: Journal Article
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