Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation. [electronic resource]
Producer: 20140408Description: 411-3 p. digitalISSN:- 1476-5551
- Acetylation -- drug effects
- Antimetabolites, Antineoplastic -- pharmacology
- Azacitidine -- pharmacology
- Bone Marrow Cells -- drug effects
- Cells, Cultured
- DNA Methylation -- drug effects
- Epigenesis, Genetic -- drug effects
- Epigenomics
- Histones -- metabolism
- Humans
- Myelodysplastic Syndromes -- genetics
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Publication Type: Letter
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