High-dose cholecalciferol supplementation significantly increases peripheral CD4⁺ Tregs in healthy adults without negatively affecting the frequency of other immune cells. [electronic resource]
Producer: 20150212Description: 751-9 p. digitalISSN:- 1436-6215
- Adjuvants, Immunologic -- administration & dosage
- Adult
- Apoptosis
- Austria
- Blood Cell Count
- CD4 Antigens -- blood
- Calcifediol -- blood
- Cells, Cultured
- Cholecalciferol -- administration & dosage
- Coculture Techniques
- Dietary Supplements -- adverse effects
- Double-Blind Method
- Female
- Forkhead Transcription Factors -- blood
- Humans
- Interleukin-2 Receptor alpha Subunit -- blood
- Leukocytes, Mononuclear -- cytology
- Leukopoiesis
- Male
- T-Lymphocytes, Regulatory -- cytology
- Vitamin D Deficiency -- blood
- Young Adult
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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