Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster. [electronic resource]
Producer: 20140902Description: 1155-1163 p. digitalISSN:- 1873-4596
- Aging -- drug effects
- Albumins -- chemistry
- Animals
- Animals, Genetically Modified
- Cathepsin B -- biosynthesis
- Cathepsin D -- genetics
- Cathepsin L -- biosynthesis
- Diet
- Drosophila melanogaster -- metabolism
- Fructose -- chemistry
- Glucose -- chemistry
- Glycation End Products, Advanced -- administration & dosage
- Glycosylation
- Lipofuscin -- administration & dosage
- Longevity -- drug effects
- Oxidation-Reduction
- Oxidative Stress -- drug effects
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- Protein Folding -- drug effects
- RNA Interference
- RNA, Small Interfering
- Ribose -- chemistry
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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