Targeting EP4 by curcumin through cross talks of AMP-dependent kinase alpha and p38 mitogen-activated protein kinase signaling: the role of PGC-1α and Sp1. [electronic resource]
Producer: 20141203Description: 2566-74 p. digitalISSN:- 1873-3913
- Adenylate Kinase -- metabolism
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Curcumin -- pharmacology
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Head and Neck Neoplasms -- drug therapy
- Humans
- Metformin -- pharmacology
- Molecular Targeted Therapy
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
- RNA Interference
- Receptors, Prostaglandin E, EP4 Subtype -- genetics
- Signal Transduction -- drug effects
- Transcription Factors -- genetics
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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