Novel BACE1 inhibitors with a non-acidic heterocycle at the P1' position. [electronic resource]
Producer: 20140526Description: 6665-73 p. digitalISSN:- 1464-3391
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Benzamides -- chemical synthesis
- Heterocyclic Compounds -- chemical synthesis
- Humans
- Hydrogen Bonding
- Protease Inhibitors -- chemical synthesis
- Protein Binding
- Quantitative Structure-Activity Relationship
- Recombinant Proteins -- biosynthesis
- Thiadiazoles -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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