Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. [electronic resource]
Producer: 20131104Description: 1355-64 p. digitalISSN:- 1460-2105
- Animals
- Apoptosis
- Arginine
- Ataxia Telangiectasia Mutated Proteins
- Carcinoma, Renal Cell -- genetics
- Cell Cycle Proteins -- metabolism
- DNA Damage
- DNA-Binding Proteins -- metabolism
- Embryonic Stem Cells
- Glutamine
- Humans
- Hypoxia-Inducible Factor 1 -- metabolism
- Immunohistochemistry
- Kidney Neoplasms -- genetics
- Mice
- Occupational Exposure
- Point Mutation
- Proline
- Protein Array Analysis
- Protein Serine-Threonine Kinases -- metabolism
- Serine
- Teratoma -- genetics
- Trichloroethylene -- toxicity
- Tumor Suppressor Proteins -- metabolism
- Ubiquitin-Protein Ligases -- metabolism
- Von Hippel-Lindau Tumor Suppressor Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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