Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding. [electronic resource]
Producer: 20131210Description: 14995-5000 p. digitalISSN:- 1091-6490
- Amino Acid Substitution
- Animals
- Animals, Genetically Modified
- Brain -- metabolism
- Cation Transport Proteins -- antagonists & inhibitors
- Copper -- administration & dosage
- Copper-Transporting ATPases
- Disease Models, Animal
- Drosophila Proteins -- antagonists & inhibitors
- Drosophila melanogaster -- genetics
- Female
- Gene Expression
- Genes, Insect
- Humans
- Huntingtin Protein
- Huntington Disease -- etiology
- Nerve Tissue Proteins -- genetics
- Peptides -- genetics
- Protein Binding
- RNA Interference
- Recombinant Proteins -- genetics
- Trinucleotide Repeat Expansion
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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