The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. [electronic resource]
Producer: 20131209Description: 4166-80 p. digitalISSN:- 1098-5549
- Amino Acid Sequence
- Anaphase-Promoting Complex-Cyclosome -- metabolism
- Cdc20 Proteins -- metabolism
- Conserved Sequence
- G2 Phase Cell Cycle Checkpoints
- Gene Expression Regulation
- HEK293 Cells
- HeLa Cells
- Histone Demethylases -- chemistry
- Humans
- MCF-7 Cells
- Mitosis
- Mutation, Missense
- Proteasome Endopeptidase Complex
- Protein Binding
- Protein Interaction Domains and Motifs
- Protein Interaction Mapping
- Proteolysis
- S Phase Cell Cycle Checkpoints
- Transcription Factors -- chemistry
- Transcription, Genetic
- Ubiquitination
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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