Heterozygous disruption of activin receptor-like kinase 1 is associated with increased renal fibrosis in a mouse model of obstructive nephropathy. [electronic resource]
Producer: 20140929Description: 319-32 p. digitalISSN:- 1523-1755
- Actins -- metabolism
- Activin Receptors, Type I -- deficiency
- Activin Receptors, Type II
- Animals
- Biomarkers -- metabolism
- Cell Proliferation
- Cells, Cultured
- Collagen Type I -- metabolism
- Disease Models, Animal
- Extracellular Matrix -- metabolism
- Fibronectins -- metabolism
- Fibrosis
- Haploinsufficiency
- Heterozygote
- Kidney -- enzymology
- Kidney Diseases -- enzymology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Myofibroblasts -- enzymology
- S100 Calcium-Binding Protein A4
- S100 Proteins -- metabolism
- Signal Transduction
- Smad Proteins -- metabolism
- Time Factors
- Transforming Growth Factor beta -- metabolism
- Ureteral Obstruction -- complications
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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