Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer. [electronic resource]
Producer: 20140114Description: 195-203 p. digitalISSN:- 1872-7980
- Animals
- Blotting, Western
- Cadherins -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Curcumin -- analogs & derivatives
- Cytosine -- metabolism
- DNA (Cytosine-5-)-Methyltransferase 1
- DNA (Cytosine-5-)-Methyltransferases -- genetics
- DNA Methylation -- drug effects
- Dose-Response Relationship, Drug
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- HSP90 Heat-Shock Proteins -- genetics
- Humans
- Immunohistochemistry
- Mice
- Mice, Nude
- Osteonectin -- genetics
- Pancreatic Neoplasms -- drug therapy
- Piperidones -- pharmacology
- Pyridines
- Reverse Transcriptase Polymerase Chain Reaction
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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