Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities. [electronic resource]
Producer: 20140227Description: 2164 p. digitalISSN:- 2041-1723
- Biocatalysis
- Conserved Sequence
- Crystallography, X-Ray
- Glutamic Acid -- metabolism
- Glycoside Hydrolases -- chemistry
- Humans
- Hydrolysis
- Models, Molecular
- Molecular Dynamics Simulation
- Mutagenesis
- Poly Adenosine Diphosphate Ribose -- chemistry
- Substrate Specificity
- Tetrahymena thermophila -- enzymology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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