Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma. [electronic resource]
Producer: 20140303Description: 190-201 p. digitalISSN:- 1527-3350
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- drug therapy
- Catalytic Domain
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Humans
- Liver Neoplasms -- drug therapy
- Mice
- Models, Molecular
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds -- pharmacology
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- chemistry
- Random Allocation
- STAT3 Transcription Factor -- antagonists & inhibitors
- Sorafenib
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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