Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis. [electronic resource]
Producer: 20140607Description: 1158-71 p. digitalISSN:- 1949-2553
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Carbazoles -- pharmacology
- Cell Growth Processes -- drug effects
- Cell Line, Tumor
- Female
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- M Phase Cell Cycle Checkpoints -- drug effects
- MAP Kinase Kinase Kinases
- MAP Kinase Signaling System -- drug effects
- MCF-7 Cells
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Molecular Targeted Therapy
- Protein Kinase Inhibitors -- pharmacology
- Receptors, Estrogen -- biosynthesis
- Transfection
- Mitogen-Activated Protein Kinase Kinase Kinase 11
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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