Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2α phosphorylation, and the induction of downstream targets. [electronic resource]
Producer: 20140312Description: 745-57 p. digitalISSN:- 1525-2191
- Activating Transcription Factor 4 -- metabolism
- Amino Acids -- biosynthesis
- Animals
- Apoptosis
- Autophagy
- Cardiomegaly -- pathology
- Disease Models, Animal
- Eukaryotic Initiation Factor-2 -- metabolism
- Female
- Friedreich Ataxia -- diagnostic imaging
- Gene Expression Profiling
- Heart Function Tests
- Humans
- Iron-Binding Proteins -- metabolism
- Male
- Mice
- Mice, Knockout
- Models, Biological
- Myocardium -- metabolism
- Myocytes, Cardiac -- enzymology
- Phenotype
- Phosphorylation
- Protein Kinases -- metabolism
- Signal Transduction -- genetics
- Stress, Physiological -- genetics
- Ultrasonography
- Frataxin
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.