Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase. [electronic resource]
Producer: 20140519Description: 2135-44 p. digitalISSN:- 1538-8514
- Apoptosis -- genetics
- Cell Line, Tumor
- DNA Breaks, Double-Stranded
- DNA Repair -- genetics
- DNA Repair Enzymes -- antagonists & inhibitors
- Gene Knockout Techniques
- HCT116 Cells
- Humans
- Molecular Targeted Therapy
- Neoplasms -- drug therapy
- PTEN Phosphohydrolase -- genetics
- Phosphotransferases (Alcohol Group Acceptor) -- antagonists & inhibitors
- RNA, Small Interfering
- Radiation Tolerance -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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