Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. [electronic resource]
Producer: 20131104Description: E2950-7 p. digitalISSN:- 1091-6490
- AMP-Activated Protein Kinase Kinases
- AMP-Activated Protein Kinases -- metabolism
- Animals
- Ataxia Telangiectasia Mutated Proteins
- Autophagy -- drug effects
- Blotting, Western
- Cell Cycle Proteins -- genetics
- Cells, Cultured
- DNA-Binding Proteins -- genetics
- Embryo, Mammalian -- cytology
- Fibroblasts -- cytology
- HeLa Cells
- Humans
- MCF-7 Cells
- Mice
- Mice, Knockout
- Models, Biological
- Multiprotein Complexes -- metabolism
- Nitric Oxide -- metabolism
- Nitric Oxide Donors -- metabolism
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- genetics
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Spermine -- analogs & derivatives
- TOR Serine-Threonine Kinases -- metabolism
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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