Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. [electronic resource]
Producer: 20140130Description: 2189 p. digitalISSN:- 2041-1723
- Animals
- Apoptosis -- genetics
- Apoptosis Regulatory Proteins -- genetics
- Autophagy -- genetics
- Beclin-1
- Cell Communication
- Cell Line, Tumor
- Gene Expression Regulation
- Humans
- Membrane Proteins -- genetics
- Mice
- Mice, Transgenic
- Phagosomes -- metabolism
- Phosphorylation
- Protein Binding
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Small Interfering -- genetics
- Signal Transduction
- Stress, Physiological
- Tumor Suppressor Proteins -- genetics
- rho-Associated Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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