Association of CYP2C9*2 with bosentan-induced liver injury. [electronic resource]
Producer: 20140113Description: 678-86 p. digitalISSN:- 1532-6535
- Alanine Transaminase -- metabolism
- Aryl Hydrocarbon Hydroxylases -- genetics
- Aspartate Aminotransferases -- metabolism
- Bosentan
- Chemical and Drug Induced Liver Injury -- enzymology
- Cytochrome P-450 CYP2C9
- Endothelin Receptor Antagonists
- Female
- Genetic Association Studies
- Genetic Markers
- HEK293 Cells
- Humans
- Hypertension, Pulmonary -- drug therapy
- Liver-Specific Organic Anion Transporter 1
- Male
- Middle Aged
- Multidrug Resistance-Associated Protein 2
- Organic Anion Transporters -- genetics
- Polymorphism, Single Nucleotide
- Sulfonamides -- adverse effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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