Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. [electronic resource]
Producer: 20140408Description: 285-99 p. digitalISSN:- 1875-9777
- Animals
- Bone Marrow -- physiology
- Cell Transdifferentiation
- Cells, Cultured
- Chemokine CCL3 -- metabolism
- Hematopoietic Stem Cell Transplantation
- Humans
- Leukemia -- complications
- Mesenchymal Stem Cells -- physiology
- Mice
- Mice, Transgenic
- Myeloproliferative Disorders -- complications
- Neoplastic Stem Cells -- physiology
- Primary Myelofibrosis -- etiology
- Receptors, Notch -- metabolism
- Stem Cell Niche
- Thrombopoietin -- metabolism
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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