Severe irinotecan-induced toxicity in a patient with UGT1A1 28 and UGT1A1 6 polymorphisms. [electronic resource]
Producer: 20140123Description: 3899-903 p. digitalISSN:- 2219-2840
- Adenocarcinoma -- drug therapy
- Aged
- Antineoplastic Agents, Phytogenic -- adverse effects
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Camptothecin -- adverse effects
- Colonic Neoplasms -- drug therapy
- Diarrhea -- chemically induced
- Dose-Response Relationship, Drug
- Fluorouracil -- adverse effects
- Glucuronosyltransferase -- genetics
- Heterozygote
- Humans
- Irinotecan
- Leucovorin -- adverse effects
- Male
- Neutropenia -- chemically induced
- Polymorphism, Genetic -- genetics
- Severity of Illness Index
- Treatment Outcome
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Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
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