V8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma. [electronic resource]
Producer: 20141028Description: 97-107 p. digitalISSN:- 1432-0738
- Animals
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- drug therapy
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Endoplasmic Reticulum Chaperone BiP
- Endoplasmic Reticulum Stress -- drug effects
- Female
- Flavanones -- chemistry
- Flavones -- chemical synthesis
- Hep G2 Cells -- drug effects
- Humans
- Inhibitory Concentration 50
- Liver Neoplasms -- drug therapy
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Transcription Factor CHOP -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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