Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling. [electronic resource]
Producer: 20130930Description: 1287-99 p. digitalISSN:- 1550-6606
- Adrenal Cortex Hormones -- metabolism
- Aged
- Aspergillosis -- immunology
- Aspergillus fumigatus -- immunology
- Autophagy -- immunology
- Autophagy-Related Protein 5
- Cells, Cultured
- Female
- Granulomatous Disease, Chronic -- immunology
- Humans
- Intracellular Signaling Peptides and Proteins -- metabolism
- Lectins, C-Type -- metabolism
- Leukocytes, Mononuclear -- immunology
- Microtubule-Associated Proteins -- drug effects
- Middle Aged
- Phagosomes -- immunology
- Phosphorylation -- drug effects
- Protein-Tyrosine Kinases -- metabolism
- RNA Interference
- RNA, Small Interfering
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Syk Kinase
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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