Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. [electronic resource]
Producer: 20140326Description: 201-7 p. digitalISSN:- 1872-7573
- Animals
- Aromatase -- metabolism
- Aromatase Inhibitors -- isolation & purification
- Cells, Cultured
- Ethnopharmacology
- Eurycoma -- chemistry
- Leydig Cells -- drug effects
- Male
- Molecular Docking Simulation
- Phosphodiesterase Inhibitors -- isolation & purification
- Phosphoric Diester Hydrolases -- metabolism
- Plant Extracts -- isolation & purification
- Plant Roots -- chemistry
- Protein Binding
- Quassins -- isolation & purification
- Rats
- Rats, Sprague-Dawley
- Spermatogenesis -- drug effects
- Testosterone -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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