A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells. [electronic resource]
Producer: 20141215Description: 128-36 p. digitalISSN:- 1879-3169
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Breast Neoplasms -- metabolism
- Caspase 3 -- genetics
- Caspase 7 -- genetics
- Cell Line, Tumor
- Cytochromes c -- genetics
- Dioxoles -- pharmacology
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- MCF-7 Cells
- Mitochondria -- drug effects
- Mitochondrial Proteins -- genetics
- Reactive Oxygen Species -- metabolism
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- genetics
- Tetrahydroisoquinolines -- pharmacology
- Trabectedin
- bcl-2-Associated X Protein -- genetics
- bcl-Associated Death Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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