Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells. [electronic resource]
Producer: 20131001Description: 79-86 p. digitalISSN:- 1090-2104
- Adenosine -- analogs & derivatives
- Adenosine A3 Receptor Agonists -- chemistry
- Animals
- Biomarkers -- metabolism
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Embryoid Bodies -- cytology
- Embryonic Stem Cells -- cytology
- Enzyme Activation -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- In Vitro Techniques
- Mice
- Neovascularization, Physiologic -- drug effects
- Phosphatidylinositol 3-Kinases -- metabolism
- Platelet Endothelial Cell Adhesion Molecule-1 -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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