TNFα-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation. [electronic resource]
Producer: 20140425Description: 4015-25 p. digitalISSN:- 1477-9137
- Animals
- Apoptosis
- Apoptotic Protease-Activating Factor 1 -- deficiency
- Caspase 3 -- deficiency
- Caspase 7 -- deficiency
- Caspase 9 -- deficiency
- Cathepsin B -- deficiency
- Cathepsin L -- deficiency
- Cell Membrane -- metabolism
- Cell Membrane Permeability -- physiology
- Cycloheximide -- pharmacology
- Electron Transport Complex I -- metabolism
- Enzyme Activation
- HeLa Cells
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mitochondria -- metabolism
- Mitochondrial Membranes -- metabolism
- NADH Dehydrogenase -- biosynthesis
- Organophosphorus Compounds -- pharmacology
- Protein Synthesis Inhibitors -- pharmacology
- Reactive Oxygen Species
- Tumor Necrosis Factor-alpha -- metabolism
- Ubiquinone -- analogs & derivatives
- bcl-2 Homologous Antagonist-Killer Protein -- deficiency
- bcl-2-Associated X Protein -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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