Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. [electronic resource]
Producer: 20130926Description: 11115-20 p. digitalISSN:- 1091-6490
- Animals
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Benzo(a)pyrene -- toxicity
- Bone Resorption -- etiology
- Carcinogens -- toxicity
- Cytochrome P-450 CYP1A1 -- biosynthesis
- Cytochrome P-450 CYP1A2 -- biosynthesis
- Cytochrome P-450 CYP1B1
- Disease Models, Animal
- Enzyme Induction -- genetics
- Female
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Polychlorinated Dibenzodioxins -- toxicity
- Receptors, Aryl Hydrocarbon -- deficiency
- Smoke -- adverse effects
- Smoking -- adverse effects
- Nicotiana -- toxicity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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