β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase. [electronic resource]
Producer: 20141103Description: 793-806 p. digitalISSN:- 1098-2744
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Apoptosis Regulatory Proteins -- metabolism
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Cell Proliferation -- drug effects
- Drug Screening Assays, Antitumor
- Enzyme Induction -- drug effects
- Gene Expression -- drug effects
- Humans
- Interleukin-6 -- physiology
- Janus Kinase 2 -- metabolism
- Membrane Potential, Mitochondrial
- Neoplasm Invasiveness
- Phosphorylation
- Polycyclic Sesquiterpenes
- Protein Binding
- Protein Processing, Post-Translational
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- genetics
- STAT3 Transcription Factor -- metabolism
- Sesquiterpenes -- pharmacology
- Signal Transduction
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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