Targeted mutations in a highly conserved motif of the nsp1β protein impair the interferon antagonizing activity of porcine reproductive and respiratory syndrome virus. [electronic resource]
Producer: 20131106Description: 1972-1983 p. digitalISSN:- 1465-2099
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Cell Line
- Cysteine Proteases -- genetics
- DNA Mutational Analysis
- Host-Pathogen Interactions
- Humans
- Immune Evasion
- Interferons -- antagonists & inhibitors
- Macrophages -- virology
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutant Proteins -- genetics
- Porcine respiratory and reproductive syndrome virus -- genetics
- Reverse Genetics
- Viral Nonstructural Proteins -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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