Combination of CYP inhibitor with MEK/ERK inhibitor enhances the inhibitory effect on ERK in BRAF mutant colon cancer cells. [electronic resource]
Producer: 20130813Description: 2499-508 p. digitalISSN:- 1791-7530
- Benzoflavones -- pharmacology
- Butadienes -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colonic Neoplasms -- drug therapy
- Cytochrome P-450 CYP1A1 -- antagonists & inhibitors
- Cytochrome P-450 CYP1A2 -- metabolism
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Humans
- MAP Kinase Signaling System -- drug effects
- Nitriles -- pharmacology
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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