Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors. [electronic resource]
Producer: 20140414Description: 1322-32 p. digitalISSN:- 1948-7193
- Amidohydrolases -- antagonists & inhibitors
- Animals
- Blood Glucose -- analysis
- Brain -- drug effects
- Carbamates -- chemical synthesis
- Diabetes Mellitus, Type 2 -- blood
- Diabetic Neuropathies -- blood
- Drug Evaluation, Preclinical
- Endocannabinoids -- metabolism
- HEK293 Cells
- Humans
- Hyperalgesia -- drug therapy
- Insulin -- blood
- Liver -- drug effects
- Male
- Mice
- Molecular Structure
- Monoacylglycerol Lipases -- antagonists & inhibitors
- Nociception -- drug effects
- Rats
- Rats, Sprague-Dawley
- Species Specificity
- Structure-Activity Relationship
- Succinimides -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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