The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex. [electronic resource]
Producer: 20140422Description: 4031-42 p. digitalISSN:- 1460-2083
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Bardet-Biedl Syndrome -- metabolism
- Carrier Proteins -- metabolism
- Cell Cycle Proteins -- metabolism
- Cilia -- metabolism
- Cytoskeletal Proteins
- Gene Expression Regulation
- Gene Knockdown Techniques
- HEK293 Cells
- HeLa Cells
- Humans
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Microtubule-Associated Proteins
- Multiprotein Complexes -- metabolism
- NIH 3T3 Cells
- Rapamycin-Insensitive Companion of mTOR Protein
- Signal Transduction -- physiology
- TOR Serine-Threonine Kinases -- metabolism
- Zebrafish -- embryology
- Zebrafish Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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